
moderate Efficacy
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Abnormal iron levels can be found in most children with ADHD, lower levels are associated with more severe ADHD symptoms, it stands to reason that iron supplementation may be benefit some people with ADHD.
It is estimated that around 30% of ADHD symptom severity could be associated with non-anemic iron deficiency. Some medium-sized controlled studies show significant symptom reduction strongly correlated with iron supplementation in children with ADHD. In rats, abnormal iron levels were shown to strongly correlate with lower dopamine receptor density—one possible pathway through which iron deficiency may contribute to ADHD symptoms. While this specific mechanism has yet to be confirmed in humans, we have strong evidence suggesting cognitive detriments are associated with lower childhood iron levels. Note: Monthly cycles deplete iron, reducing dopamine and ADHD medication effectiveness. Women especially should check ferritin levels and consider supplementation.